As we all age, the process of shedding skin cells and having new cells take their place slows down -- resulting in a loss of firmness and a dull, uneven skin tone. When the dormant stem cells in the skin of the face are awakened by the stem cell activator -- ActiStem^™ dermal -- the skin cells are revitalized, skin cell replacement becomes faster and the glow generated by healthy new skin becomes more apparent.

In addition to the revitalization of the skin cells and the skin cell replacement cycle, the activation of stem cells by ActiStem^™ dermal also causes an increase in production of dermal collagen and elastin. The resulting increase in the collagen-elastin matrix has a lifting and tightening effect on the skin and also gives the skin of the face a fuller, more supple look.

The uniqueness of ActiStem^™ dermal is its ability to activate the large reserves of dormant stem cells and fibroblasts in the skin of the face, neck and back of the hands owing to the signalling properties of the small peptides present in it.

ActiStem^™ dermal is natural and is a fractionated protein extract concentrate derived from the placenta of sheep. Sheep (ovine) placenta is a rich source of nutrients, growth factors and bio-active cytokines which have been found by scientific studies to promote cell growth, wound healing and to have an anti-inflammatory effect.

A clinical study into the effectiveness of ActiStem^™ dermal, performed by a dermatologist, dermatopathologist and a leading plastic surgeon on 30 subjects was completed in February, 2008.

This demonstrated a significant increase in the collagen and elastin content of the skin and correlated with a statistically significant effect in the lifting and tightening of the skin, improved radiance or glow, and a marked lessening of fine lines and wrinkles in both men and women who participated in the trial.

CAUTION:
For cosmetic use only. Not for drug, household or other uses.

Improvement in Collagen
Statistically significant increases in collagen were noted in 80% of patients after 6 weeks.

Day 0 Day 42 Microscopy of skin biopsy - collagen stain

Improvement in Elastin Fibers
A significant increase in dermal elastin was noted in 40% of patients after 6 weeks.

Day 0 Day 42 Microscopy of skin biopsy - elastin stain

ActiStem^™ dermal is supplied in boxes containing 6 x 10ml vials with a total of 30ml of the Ovine placental fractionated protein extract (OPFPE). Each vial contains 5ml of ActiStem^™ dermal and is intended for use on a single patient.

ActiStem^™ dermal is supplied to dermatologists, plastic surgeons, doctors and cosmetic practitioners. It is applied topically to the face (and neck/back of the hands if required) using a dermal roller or before/after the application of a Fraxel^™ laser.

Medical product distributors are invited to purchase sample boxes of 6 vials each.

 ActiStem^™ dermal

 Distributors Invited

 Corporate Headquarters